Risk of suicide in men with low-risk prostate cancer

A Swedish study has reported an increased risk of suicide in men diagnosed with prostate cancer. Even patients diagnosed with low-risk, early-stage disease had increased risk within the first 6 months following the diagnosis. The study was a nation-wide, population based study using the Prostate Cancer data Base in Sweden.


PCF, Sanofi initiate text message support program for men on chemotherapy

The Prostate Cancer Foundation (PCF) and Sanofi have initiated a new, one-way, text message-based support program called Prost8Care for men with advance prostate cancer to reinforce healthcare guidances on treatment, side effects, and diet.


Signaling pathway found crucial for prostate cancer cell proliferation

A pathway that was previously not well understood has been found to be crucial for growth and proliferation of prostate cancer cells, a new study finds. Soluble adenylyl cyclase (sAC) is overexpressed in prostate carcinoma and inhibition of sAC leads to cell cycle arrest. sAC represents a novel pathway promoting proliferation in cancer cells and is a promising target for prostate cancer treatment..


Work stress very unlikely to cause cancer new study shows

Work-related stress is not linked to the development of colorectal, lung, breast or prostate cancers, a new study suggests. Around 90% of cancers are linked to environmental exposures and whilst some exposures are well recognised (such as UV radiation and tobacco smoke), others are not (psychological factors such as stress).


Comparative Effectiveness of Alternative PSA–Based Prostate Cancer Screening Suggests Varying PSA Screening for Older Men May Be Beneficial

Compared with standard screening, PSA screening strategies that use higher thresholds for biopsy referral for older men and that screen men with low PSA levels less frequently can reduce harms while preserving lives.


Receptor tyrosine kinase Axl is essential regulator of prostate cancer proliferation and could be new therapeutic target

Axl is consistently overexpressed in prostate cancer cell lines and human prostate tumors. Blocking Axl gene expression strongly inhibits proliferation, migration, invasion and tumor growth researchers find. Results may have implications for new treatment development


PCF, Sanofi initiate text message support program for men on chemotherapy

The Prostate Cancer Foundation (PCF) and Sanofi have initiated a new, one-way, text message-based support program called Prost8Care for men with advance prostate cancer to reinforce healthcare guidances on treatment, side effects, and diet.


Expert Clinical Opinion on prostatic intraepithelial neoplasia (PIN)

Post two large-scale PIN-to-cancer chemoprevention trials, the authors discourage aggressive rebiopsy of patient with PIN unless a risk assessment tool suggests a high likelihood of a high-grade tumor that was missed on biopsy.


Team of scientists evaluate different ways to help make PSA screening decision

How PSA screening informtion is presented effects a man’s decision to be screened for prostate cancer. The researchers described PSA screening decision options as 4 key attributes: effect on prostate cancer mortality, risk of biopsy, risk of being diagnosed with prostate cancer and risk of becoming impotent or incontinent as a result of treatment and presented the information in 3 formats.