15-year Study in NEJM Shows Long-Term Urinary, Bowel, and Sexual Function in Men Treated by Surgery or Radiotherapy is Similar

Patients undergoing prostatectomy were more likely to have urinary incontinence than were those undergoing radiotherapy at 2 years and 5 years. But, by year 15,, there was no no significant differences between the 2 groups. The same was found for erectile dysfunction and bowel urgency.

3-D Prostate Cancer Metastasis Model Shows N-Cadherin Needed for Cell Invasion of Prostate Cancer Cells

Using a bone metastasis cell line model of prostate cancer cells in a physiologically relevant, 3D Matrigel, study results suggest that the formation of N-cadherin junctions promotes 3D cell migration of prostate cancer cells, and this is partly due to an aberrant regulation of the N-cadherin complex in the absence of α-catenin.

Deep-fried food consumption linked to prostate cancer

Men who reported eating French fries, fried chicken, fried fish and/or doughnuts at least once a week were at an increased risk (30-37% increase) of prostate cancer as compared to men who said they ate such foods less than once a month. Men who ate more of the fried foods had a higher risk of aggressive prostate cancer.

New Radiation Therapy, Volumetric Modulated Arc Therapy, Shortens Prostate Cancer Treatment Time

Single-institution study at Winship Cancer Institute of Emory University in Atlanta finds using volume-modulated arc therapy (VMAT) to deliver intensity-modulated radiation therapy (IMRT) to prostate cancer patients results in an overall reduction in treatment time of approximately 14 percent.

Risk of suicide in men with low-risk prostate cancer

A Swedish study has reported an increased risk of suicide in men diagnosed with prostate cancer. Even patients diagnosed with low-risk, early-stage disease had increased risk within the first 6 months following the diagnosis. The study was a nation-wide, population based study using the Prostate Cancer data Base in Sweden.

Hematuria can be a common, delayed side effect after prostate brachytherapy

A significant proportion of the patients with prostate cancer treated with brachytherapy develop gross hematuria several years later. Patients at highest risk for hematuria are those with a larger size prostates, patients who have additional treatment with external beam radiation, and those with biochemical PSA control after treatment.

PCF, Sanofi initiate text message support program for men on chemotherapy

The Prostate Cancer Foundation (PCF) and Sanofi have initiated a new, one-way, text message-based support program called Prost8Care for men with advance prostate cancer to reinforce healthcare guidances on treatment, side effects, and diet.

Signaling pathway found crucial for prostate cancer cell proliferation

A pathway that was previously not well understood has been found to be crucial for growth and proliferation of prostate cancer cells, a new study finds. Soluble adenylyl cyclase (sAC) is overexpressed in prostate carcinoma and inhibition of sAC leads to cell cycle arrest. sAC represents a novel pathway promoting proliferation in cancer cells and is a promising target for prostate cancer treatment..

Work stress very unlikely to cause cancer new study shows

Work-related stress is not linked to the development of colorectal, lung, breast or prostate cancers, a new study suggests. Around 90% of cancers are linked to environmental exposures and whilst some exposures are well recognised (such as UV radiation and tobacco smoke), others are not (psychological factors such as stress).