A Clinical Model for Identifying Radiosensitive Tumor Genotypes in Non-Small Cell Lung Cancer

“We examined clinical outcomes after Gamma Knife (GK) radiotherapy for NSCLC intracranial metastases to evaluate the utility of this model for determining radiosensitive tumor genotypes. This study suggests that EGFR kinase domain mutations and EML4-ALK translocations are radiosensitive NSCLC genotypes, and proposes a novel model to identify radiosensitive subtypes of NSCLC.”