“Findings from a population-based study reported at the 2016 ASCO Annual Meeting revealed that young black women with breast cancer are much less likely to undergo testing for the BRCA gene than other women. Or, if they do carry a BRCA mutation, they are less likely to get a prophylactic mastectomy or salpingo-oophorectomy to reduce the risk of developing cancer.
“The research identified disparities in recipients of BRCA testing between non-Hispanic white women, Hispanic, and black women, with the latter being the least likely to undergo testing. Likewise, black women who were BRCA carriers were less likely to undergo risk-management practices compared with their white and Hispanic counterparts.
“ ‘We need to understand the reasons for these findings,’ said lead study author Tuya Pal, MD, a clinical geneticist at the Moffitt Cancer Center in Tampa, Florida. Ultimately, it’s the patient who must decide whether to have genetic testing and take prophylactic measures for risk management, Pal said.”
Do you have questions about this story? Let us know in a comment below. If you’re wondering whether this story applies to your own cancer case or a loved one’s, we invite you to use our Ask Cancer Commons service.
Smokers with low bilirubin levels were at increased risk for lung cancer incidence and mortality compared with those who had the highest bilirubin levels, making serum bilirubin a potential biomarker for lung cancer risk prediction.
An ongoing collaboration of more than 50 research groups around the world has identified 23 new genes or genomic regions that may contribute to the development of prostate cancer. These findings allow for a more accurate assessment of a person’s risk of developing prostate cancer. The results were published in the April, 2013, issue of Nature Genetics (doi:10.1038/ng.2560).
Including the 23 new prostate cancer susceptibility genetic loci, there are now a total of 77 known loci linked to prostate cancer. This accounts for about 30% of all familial risk for prostate cancer—the other factors for familial risk for prostate cancer are not yet defined. Continue reading…