Cancer Commons Observational Study CCCS001

Methods of Identifying Effective Off-Guideline Treatments for Advanced Cancer Patients (CC N-of-1)

Scientific Evidence Report Sample

Report Page 1

Patient PHR, prior treatement history, and brief narrative on disease progression status and functional capacity for additional therapy. If available, genomic profiling results with key findings.

Report Page 2

Functional testing results with drug sensitivity table, expert interpretation box, and reference to lab report. If appropriate, justification for pursuing off-guideline therapy based on exhaustion of standard options and patient fitness.

Report Page 3

Functional test overview and predictive accuracy. Literature review.

Report Pages 4-5

Synthesis of molecular findings, functional testing, and literature evidence. Ends with recommendation statement, as appropriate.